Itumbiara's main attraction is its nautical tourism. The artificial lake Itumbiara can be used for all types of water sports. On the second Sunday of August the traditional river procession of Our Lady of the Graces takes place. Other touristic points are the Vermelhão Lake, two waterfalls, Salto de Santa Maria de Cima and Saltos de Santa Maria do Meio. The Affonso Penna Bridge, also known as the "Crystal Bridge", which links the states of Goiás and Minas Gerais. Itumbiara also has a Kart circuit, which hosts regional, national and international events, with a capacity for 5,000 people.
The city is served by Francisco Vilela do Amaral Airport.