The Kangaroo River Nature Reserve, part of the Kangaroo Valley Group of Nature Reserves, is a protected nature reserve that is located on the floor of the Kangaroo Valley in the Southern Highlands and South Coast regions of New South Wales in eastern Australia. The reserve is situated approximately 150km south of Sydney, 50km southwest of Wollongong and 16km northwest of . The reserve has a protective covenant placed upon it with purpose to ensure the protection of the natural heritage of this area. National parks in the area include the Morton National Park and the Budderoo National Park. Other nature reserves in the area include the Barren Grounds Nature Reserve, and the Cambewarra Range, Barrengarry and Rodway nature reservesthe latter three part of the Kangaroo Valley Group of Nature Reserves.