Köpetdag Nature Reserve is a nature reserve of Turkmenistan. Established in 1976 for the protection of indigenous flora and fauna, it is located in the central part of the Kopetdag Range in Ahal Province, covering an area of 497km2. It also incorporates two sanctuaries and two natural monuments:
- Mäne-Çäçe Sanctuary - established in 1976.
- Guryhowdan Sanctuary - established in 1976.
- Garaýalçy Natural Monument.
- Çarlyk Natural Monument.