Phu Luang Wildlife Sanctuary (Thai: เขตรักษาพันธุ์สัตว์ป่าภูหลวง) is a wildlife sanctuary in northern Thailand, located in the Phu Luang mountain area, in the south of Loei Province. The area around the mountain is part of the Luang Prabang montane rain forests ecoregion. It covers an area of 897 km², covering area of the tambon Pla Ba and Tha Sala of Phu Ruea District, Phon Sung, Wang Yao and I Pum of Dan Sai, Nong Ngio and Saikhao of Wang Saphung, and Phu Ho of Phu Luang District.