Presidente Epitácio is a municipality in the state of São Paulo in Brazil. The town is named after Epitácio Pessoa. The population is 43,535 (2015 est.) in an area of 1260 km². The elevation is 310 m. It is situated on the Paraná River, which forms the border with Mato Grosso do Sul here. The municipality contains the 937ha Lagoa São Paulo Reserve. It contains part of the 246800ha Great Pontal Reserve, created in 1942. It also contains 11% of the 6677ha Mico Leão Preto Ecological Station, established in 2002.
