Sudley House is a historic house in Aigburth, Liverpool, England. Built in 1824 and much modified in the 1880s, it is now a museum and art gallery which contains the collection of George Holt, a shipping-line owner and former resident, in its original setting. It includes work by Thomas Gainsborough, Joshua Reynolds, Edwin Landseer, John Everett Millais and J. M. W. Turner.
The house was bequeathed to the city of Liverpool by Holt's daughter, Emma Georgina Holt, in 1944 and is now managed by National Museums Liverpool.